:: CLDF ::

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study

Lancet Gastroenterol Hepatol. 2020 Aug 4;S2468-1253(20)30252-1.doi: 10.1016/S2468-1253(20)30252-1. Online ahead of print.

Stephen A Harrison¹, Vlad Ratziu², Jérôme Boursier³, Sven Francque⁴, Pierre Bedossa⁵, Zouher Majd⁶, Geneviève Cordonnier⁶, Fouad Ben Sudrik⁶, Raphael Darteil⁷, Roman Liebe⁸, Jérémy Magnanensi⁶, Yacine Hajji⁶, John Brozek⁶, Alice Roudot⁶, Bart Staels⁹, Dean W Hum⁶, Sophie Jeannin Megnien¹⁰, Suneil Hosmane⁶, Noémie Dam⁶, Pierre Chaumat⁶, Rémy Hanf¹¹, Quentin M Anstee¹², Arun J Sanyal¹³

Mortality of NAFLD According to the Body Composition and Presence of Metabolic Abnormalities

Hepatol Commun. 2020 May 19;4(8):1136-1148. doi: 10.1002/hep4.1534. eCollection 2020 Aug.

Pegah Golabi¹, James M Paik¹, Tamoore Arshad², Youssef Younossi³, Alita Mishra², Zobair M Younossi^1 2

The Emerging Role of Hepatocellular eNOS in Non-alcoholic Fatty Liver Disease Development

Physiol. 2020 Jul 3;11:767. doi: 10.3389/fphys.2020.00767. eCollection 2020.

Rory P Cunningham^1 2, Ryan D Sheldon³, R Scott Rector^1 2 4

Non-invasive diagnostic tools for pediatric NAFLD: where are we now?

Expert Rev Gastroenterol Hepatol. 2020 Jul 25.doi: 10.1080/17474124.2020.1801413.Online ahead of print.

Antonella Mosca¹, Nadia Panera², Annalisa Crudele², Anna Alisi²

Protocol for a phase IV, open-label feasibility study investigating non-invasive markers of hepatic fibrosis in people living with HIV-1 and non-alcoholic fatty liver disease randomised to receiving optimised background therapy (OBT) plus maraviroc or OBT alone

BMJ Open. 2020 Jul 6;10(7):e035596. doi: 10.1136/bmjopen-2019-035596.

Daniel Bradshaw¹, Yvonne Gilleece², Sumita Verma³, Iga Abramowicz³, Stephen Bremner³, Nicky Perry³

A Description of Risk Factors for Non-alcoholic Fatty Liver Disease in the Southern Community Cohort Study: A Nested Case-Control Study

Front Nutr. 2020 May 21;7:71. doi: 10.3389/fnut.2020.00071. eCollection 2020.

Sudipa Sarkar¹, Loren Lipworth^2 3, Edmond K Kabagambe^2 3, Aihua Bian^3 4, Thomas G Stewart⁴, William J Blot^2 5, T Alp Ikizler^3 6, Adriana M Hung^3 6

Baseline HOMA IR and Circulating FGF21 Levels Predict NAFLD Improvement in Patients Undergoing a Low Carbohydrate Dietary Intervention for Weight Loss: A Prospective Observational Pilot Study

Nutrients. 2020 Jul 18;12(7):E2141. doi: 10.3390/nu12072141.

Mikiko Watanabe¹, Renata Risi¹, Elisabetta Camajani¹, Savina Contini¹, Agnese Persichetti¹, Dario Tuccinardi², Ilaria Ernesti³, Stefania Mariani¹, Carla Lubrano¹, Alfredo Genco³, Giovanni Spera¹, Lucio Gnessi¹, Sabrina Basciani¹

Brain MR Spectroscopy Markers of Encephalopathy Due to Nonalcoholic Steatohepatitis

J Neuroimaging. 2020 Jul 23. doi: 10.1111/jon.12728. Online ahead of print.

Thao T Tran¹, Ke Wei¹, Soren Cole¹, Edward Mena², Marie Csete¹, Kevin S King¹

Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials

J Hepatol. 2020 Jun 28;S0168-8278(20)30399-8. doi: 10.1016/j.jhep.2020.06.025.Online ahead of print.

Beth A Davison¹, Stephen A Harrison², Gad Cotter³, Naim Alkhouri⁴, Arun Sanyal⁵, Christopher Edwards³, Jerry R Colca⁶, Julie Iwashita⁶, Gary G Koch⁷, Howard C Dittrich⁶

10.

Review article: The impact of liver-directed therapies on the atherogenic risk profile in non-alcoholic steatohepatitis

Aliment Pharmacol Ther. 2020 Jul 8. doi: 10.1111/apt.15935. Online ahead of print.

Margery A Connelly¹, Jonathan Velez Rivera², John R Guyton², Mohammad Shadab Siddiqui³, Arun J Sanyal³

11.

Evidence-based clinical advice for nutrition and dietary weight loss strategies for the management of NAFLD and NASH

Clin Mol Hepatol. 2020 Jul 17. doi: 10.3350/cmh.2020.0067. Online ahead of print.

Theresa J Hydes¹, Sujan Ravi¹, Rohit Loomba², Meagan E Gray¹

12.

Lean Americans With Nonalcoholic Fatty Liver Disease Have Lower Rates of Cirrhosis and Co-morbid Diseases

Ethan M Weinberg¹, Huy N Trinh², Roberto J Firpi³, Kalyan Ram Bhamidimarri⁴, Samuel Klein⁵, Jonathan Durlam⁶, Stephanie Watkins⁶, K Rajender Reddy¹, Michael Weiss⁷, Richard C Zink⁶, Anna S Lok⁸

Clin Gastroenterol Hepatol. 2020 Jul 3;S1542-3565(20)30930-7. doi:10.1016/j.cgh.2020.06.066.Online ahead of print.

13.

Clinical assessment for high-risk patients with non-alcoholic fatty liver disease in primary care and diabetology practices

Aliment Pharmacol Ther. 2020 Aug;52(3):513-526. doi: 10.1111/apt.15830. Epub 2020 Jun 29.

Zobair M Younossi¹, Kathleen E Corey², Naim Alkhouri³, Mazen Noureddin⁴, Ira Jacobson⁵, Brian Lam¹, Stephen Clement¹, Rita Basu⁶, Stuart Gordon⁷, Natarajan Ravendhra⁸, Puneet Puri⁹, Mary Rinella¹⁰, Peter Scudera¹, Ashwani K Singal¹¹, Linda Henry¹², US Members of the Global Nash Council

14.

Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial

Am J Gastroenterol. 2020 Jul;115(7):1055-1065. doi: 10.14309/ajg.0000000000000661.

Laura Craven¹, Adam Rahman^2 3, Seema Nair Parvathy⁴, Melanie Beaton^2 3, Justin Silverman⁵, Karim Qumosani^2 3, Irene Hramiak^2 6, Rob Hegele^2 6 7, Tisha Joy^2 6, Jon Meddings⁸, Brad Urquhart², Ruth Harvie⁹, Charles McKenzie^2 7, Kelly Summers^1 2, Gregor Reid^1 2 9, Jeremy P Burton^1 2 9, Michael Silverman^1 2 4

15.

Mechanisms, screening modalities and treatment options for individuals with non-alcoholic fatty liver disease and type 2 diabetes

Diabet Med. 2020 Jul 3. doi: 10.1111/dme.14356. Online ahead of print.

T J Hydes¹, N Summers², E Brown^3 4, U Alam^3 4 5, H Thomaides-Brears⁶, J P H Wilding^3 4, D J Cuthbertson^3 4

16.

Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; The APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study)

Hepatol Int. 2020 Jul 4;1-11.doi: 10.1007/s12072-020-10072-8. Online ahead of print.

Shiv Kumar Sarin¹, Ashok Choudhury², George K Lau³, Ming-Hua Zheng^3 4, Dong Ji^3 5, Sherief Abd-Elsalam⁶, Jaeseok Hwang⁷, Xiaolong Qi⁸, Ian Homer Cua⁹, Jeong Ill Suh¹⁰, Jun Gi Park¹⁰, Opass Putcharoen¹¹, Apichat Kaewdech¹², Teerha Piratvisuth¹², Sombat Treeprasertsuk¹¹, Sooyoung Park¹³, Salisa Wejnaruemarn¹¹, Diana A Payawal¹⁴, Oidov Baatarkhuu¹⁵, Sang Hoon Ahn¹⁶, Chang Dong Yeo¹⁶, Uzziel Romar Alonzo¹⁴, Tserendorj Chinbayar¹⁷, Imelda M Loho¹⁸, Osamu Yokosuka¹⁹, Wasim Jafri²⁰, Soeksiam Tan²¹, Lau Ing Soo²¹, Tawesak Tanwandee²², Rino Gani²³, Lovkesh Anand²⁴, Eslam Saber Esmail⁶, Mai Khalaf⁶, Shahinul Alam²⁵, Chun-Yu Lin²⁶, Wan-Long Chuang²⁶, A S Soin²⁷, Hitendra K Garg²⁸, Kemal Kalista²⁹, Badamnachin Batsukh¹⁵, Hery Djagat Purnomo³⁰, Vijay Pal Dara³¹, Pravin Rathi³², Mamun Al Mahtab²⁵, Akash Shukla³³, Manoj K Sharma², Masao Omata^34 35, APASL COVID Task Force, APASL COVID Liver Injury Spectrum Study (APCOLIS Study-NCT 04345640)

17.

Role of Extracellular Vesicles in the Pathophysiology, Diagnosis and Tracking of Non-Alcoholic Fatty Liver Disease

J Clin Med. 2020 Jun 29;9(7):E2032. doi: 10.3390/jcm9072032.

Lauren A Newman¹, Michael J Sorich¹, Andrew Rowland¹

J Clin Med. 2020 Jun 29;9(7):E2032. doi: 10.3390/jcm9072032.

Lauren A Newman¹, Michael J Sorich¹, Andrew Rowland¹

18.

Health Care Use and Costs Among Patients With Nonalcoholic Steatohepatitis With Advanced Fibrosis Using the Fibrosis-4 Score

Hepatol Commun.. 2020 May 26;4(7):998-1011. doi: 10.1002/hep4.1524. eCollection 2020 Jul.

Stuart C Gordon¹, Nandita Kachru², Emily Parker³, Stephanie Korrer³, A Burak Ozbay², Robert J Wong⁴

19.

Evolving Role for Pharmacotherapy in NAFLD/NASH

Clin Transl Sci. 2020 Jun 25. doi: 10.1111/cts.12839. Online ahead of print.

Suzanna L Attia¹, Samir Softic^1 2 3, Marialena Mouzaki⁴

20.

Nonalcoholic Fatty Liver Disease (NAFLD) Is an Independent Risk Factor for Nephrolithiasis in Women: Findings From NHANES III

J Endourol. 2020 Jun 22.doi: 10.1089/end.2020.0486. Online ahead of print.

Rourke Douglas Decker¹, Eric M Ghiraldi², Alexandra H Weiss³, John P Gaughan⁴, Justin I Friedlander^5 6

21.

Dysregulated Neurovascular Control Underlies Declining Microvascular Functionality in People With Non-alcoholic Fatty Liver Disease (NAFLD) at Risk of Liver Fibrosis

Front Physiol. 2020 Jun 3;11:551. doi: 10.3389/fphys.2020.00551. eCollection 2020.

Geraldine F Clough¹, Andrew J Chipperfield², Marjola Thanaj², Eleonora Scorletti^1 3 4, Philip C Calder^1 3, Christopher D Byrne^1 3

22.

Cirrhosis in a Young Child Due to Fatty Liver; Importance of Early Screening: A Case Report and Review of the Literature

Am J Case Rep. 2020 Jun 25;21:e923250. doi: 10.12659/AJCR.923250.

Hamza Hassan Khan¹, Christine E Klingert^1 2, Sanjay Kumar^2 3, Hernando Lyons^2 3

23.

COVID-19 and Nonalcoholic Fatty Liver Disease: Two Intersecting Pandemics

Eur J Clin Invest. 2020 Jun 26;e13338. doi: 10.1111/eci.13338. Online ahead of print.

Piero Portincasa¹, Marcin Krawczyk^2 3, Wiktor Smyk⁴, Frank Lammert², Agostino Di Ciaula¹

24.

A Systematic Review of Newer Antidiabetic Agents in the Treatment of Nonalcoholic Fatty Liver Disease

Ann Pharmacother. 2020 Jun 22;1060028020935105. doi: 10.1177/1060028020935105.Online ahead of print.

John A Dougherty¹, Erenie Guirguis¹, Krisy-Ann Thornby¹

25.

Nonalcoholic Steatohepatitis Is the Most Rapidly Increasing Indication for Liver Transplantation in the United States

Gastroenterol Hepatol. 2020 Jun 9;S1542-3565(20)30775-8.doi: 10.1016/j.cgh.2020.05.064. Online ahead of print.

Zobair M Younossi¹, Maria Stepanova², Janus Ong³, Greg Trimble⁴, Saleh AlQahtani⁵, Issah Younossi², Aijaz Ahmed⁶, Andrei Racila⁷, Linda Henry²

26.

Selonsertib for Patients With Bridging Fibrosis or Compensated Cirrhosis Due to NASH: Results From Randomized Phase III STELLAR Trials

Hepatol. 2020 Jul;73(1):26-39. doi: 10.1016/j.jhep.2020.02.027. Epub 2020 Mar 6.

Stephen A Harrison¹, Vincent Wai-Sun Wong², Takeshi Okanoue³, Natalie Bzowej⁴, Raj Vuppalanchi⁵, Ziad Younes⁶, Anita Kohli⁷, Shiv Sarin⁸, Stephen H Caldwell⁹, Naim Alkhouri¹⁰, Mitchell L Shiffman¹¹, Marianne Camargo¹², Georgia Li¹², Kathryn Kersey¹², Catherine Jia¹², Yanni Zhu¹², C Stephen Djedjos¹², G Mani Subramanian¹², Robert P Myers¹², Nadege Gunn¹³, Aasim Sheikh¹⁴, Quentin M Anstee¹⁵, Manuel Romero-Gomez¹⁶, Michael Trauner¹⁷, Zachary Goodman¹⁸, Eric J Lawitz¹⁰, Zobair Younossi¹⁸, STELLAR-3 and STELLAR-4 Investigators

27.

Development of an Algorithm to Identify Cases of Nonalcoholic Steatohepatitis Cirrhosis in the Electronic Health Record

Dig Dis Sci. 2020 Jun 13. doi: 10.1007/s10620-020-06388-y. Online ahead of print.

Christopher J Danford¹, Jennifer Y Lee², Ian A Strohbehn³, Kathleen E Corey³, Michelle Lai⁴

28.

From NAFLD to MAFLD: Implications of a Premature Change in Terminology

Hepatology. 2020 Jun 16. doi: 10.1002/hep.31420. Online ahead of print.

Zobair M Younossi^1 2, Mary E Rinella³, Arun Sanyal⁴, Stephen A Harrison⁵, Elizabeth Brunt⁶, Zachary Goodman^1 2, David E Cohen⁷, Rohit Loomba⁸

29.

Novel Antisense Inhibition of Diacylglycerol O-acyltransferase 2 for Treatment of Non-Alcoholic Fatty Liver Disease: A Multicentre, Double-Blind, Randomised, Placebo-Controlled Phase 2 Trial

Lancet Gastroenterol Hepatol. 2020 Jun 15;S2468-1253(20)30186-2.doi: 10.1016/S2468-1253(20)30186-2. Online ahead of print.

Rohit Loomba¹, Erin Morgan², Lynnetta Watts², Shuting Xia², Lisa A Hannan², Richard S Geary², Brenda F Baker², Sanjay Bhanot²

30.

Effect of Gut Microbiota and PNPLA3 rs738409 Variant on Non-Alcoholic Fatty Liver Disease (NAFLD) in Obese Youth

J Clin Endocrinol Metab. 2020 Jun 19;dgaa382. doi: 10.1210/clinem/dgaa382.Online ahead of print.

Ayesha Monga Kravetz^1 2, Todd Testerman³, Brittany Galuppo², Joerg Graf³, Bridget Pierpont², Stephan Siebel², Richard Feinn¹, Nicola Santoro^2 4

31.

Effect of TSH on Non-Alcoholic Fatty Liver Disease (NAFLD) Independent of Obesity in Children of Predominantly Hispanic/Latino Ancestry by Causal Mediation Analysis

PLoS One. 2020 Jun 22;15(6):e0234985. doi: 10.1371/journal.pone.0234985. eCollection 2020.

Presley H Nichols¹, Yue Pan², Benjamin May³, Martina Pavlicova², John C Rausch^1 4, Ali A Mencin⁴, Vidhu V Thaker⁴

32.

Non-alcoholic Fatty Liver Disease in Pregnancy Is Associated With Adverse Maternal and Perinatal Outcomes

J Hepatol. 2020 Apr 15;S0168-8278(20)30215-4. doi: 10.1016/j.jhep.2020.03.049.Online ahead of print.

Monika Sarkar¹, Joshua Grab², Jennifer L Dodge³, Erica P Gunderson⁴, Jessica Rubin⁵, Roxanna A Irani⁶, Marcelle Cedars⁷, Norah Terrault⁸

33.

Use of Metabolic Syndrome Severity to Assess Treatment With Vitamin-E and Pioglitazone for Non-alcoholic Steatohepatitis

Gastroenterol Hepatol. 2020 Jun 7. doi: 10.1111/jgh.15131. Online ahead of print.

Matthew J Gurka¹, Jasmine A Mack¹, Xiaofei Chi¹, Mark D DeBoer²

34.

Biopsy Rate and Nonalcoholic Steatohepatitis (NASH) in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

Scand J Gastroenterol. 2020 Jun 1;1-6. doi: 10.1080/00365521.2020.1766554.Online ahead of print.

Florian Gerhardt¹, David Petroff², Valentin Blank^1 3, Albrecht Böhlig¹, Florian van Bömmel¹, Christian Wittekind⁴, Thomas Berg¹, Thomas Karlas¹, Johannes Wiegand¹

35.

Nonalcoholic Fatty Liver Disease and Type 2 Diabetes: Where Do Diabetologists Stand?

Clin Diabetes Endocrinol. 2020 Jun 5;6:9. doi: 10.1186/s40842-020-00097-1.eCollection 2020.

Shaheen Tomah^1 2, Naim Alkhouri³, Osama Hamdy^1 2

36.

Prediction of Advanced Fibrosis in Non-Alcoholic Fatty Liver Disease Using Gut Microbiota-Based Approaches Compared With Simple Non-Invasive Tools

Sci Rep. 2020 Jun 10;10(1):9385. doi: 10.1038/s41598-020-66241-0.

Sonja Lang^1 2, Fedja Farowski^3 4 5, Anna Martin¹, Hilmar Wisplinghoff^6 7 8, Maria J G T Vehreschild^3 4 5, Marcin Krawczyk^9 10, Angela Nowag^6 8, Anne Kretzschmar⁶, Claus Scholz⁶, Philipp Kasper¹, Christoph Roderburg¹¹, Frank Lammert⁹, Tobias Goeser¹, Hans-Michael Steffen¹, Münevver Demir^12 13

37.

Nonalcoholic Fatty Liver Disease: An Important Consideration for Primary Care Providers in Hawai

Hawaii J Health Soc Welf. 2020 Jun 1;79(6):180-186.

Robert J Pattison¹, James Phillip Esteban², Tomoki Sempokuya³, Jakrin Kewcharoen¹, Sumodh Kalathil⁴, Scott K Kuwada⁵

38.

Noninvasive Tests in the Assessment of NASH and NAFLD Fibrosis: Now and Into the Future

Semin Liver Dis. 2020 Jun 11. doi: 10.1055/s-0040-1713006. Online ahead of print.

Leon A Adams^1 2, Wah-Kheong Chan³

39.

Burden of Nonalcoholic Fatty Liver Disease in Canada, 2019-2030: A Modelling Study

CMAJ Open. 2020 Jun 9;8(2):E429-E436. doi: 10.9778/cmajo.20190212. Print Apr-Jun 2020.

Mark G Swain¹, Alnoor Ramji¹, Keyur Patel¹, Giada Sebastiani¹, Abdel Aziz Shaheen¹, Edward Tam¹, Paul Marotta¹, Magdy Elkhashab¹, Harpreet S Bajaj¹, Chris Estes², Homie Razavi¹

40.

Utilization of Hepatocellular Carcinoma Surveillance in Patients With Cirrhosis: A Systematic Review and Meta-Analysis

Hepatology. 2020 May 8.doi: 10.1002/hep.31309. Online ahead of print.

Erin Wolf¹, Nicole E Rich¹, Jorge A Marrero¹, Neehar Parikh², Amit G Singal¹

41.

Natural History of Non-Alcoholic Fatty Liver Disease: A Study With Paired Liver Biopsies

Clin Exp Hepatol. May-Jun 2020;10(3):245-254. doi: 10.1016/j.jceh.2019.07.002.Epub 2019 Jul 15.

Yala K Reddy¹, Hemnishil K Marella¹, Yu Jiang², Surosree Ganguli³, Peter Snell¹, Pradeep S B Podila⁴, Benedict Maliakkal¹, Sanjaya K Satapathy⁵

42.

Advances in Non-Invasive Biomarkers for the Diagnosis and Monitoring of Non-Alcoholic Fatty Liver Disease

Metabolism. 2020 May 5;154259. doi: 10.1016/j.metabol.2020.154259.Online ahead of print.

Michelle T Long¹, Sanil Gandhi², Rohit Loomba³

43.

Genetic Determinants of Cirrhosis and Hepatocellular Carcinoma Due to Fatty Liver Disease: What

Hepatology. 2020 Jun 7. doi: 10.1002/hep.31413. Online ahead of print.

Ruth M Pfeiffer¹, Yaron Rotman², Thomas R O'Brien¹

44.

Comparison of MAFLD and NAFLD Diagnostic Criteria in Real World

Liver Int .2020 Jun 1. doi: 10.1111/liv.14548. Online ahead of print.

Su Lin¹, Jiaofeng Huang¹, Mingfang Wang¹, Rahul Kumar², Yuxiu Liu¹, Shiying Liu¹, Yinlian Wu¹, Xiaozhong Wang³, Yueyong Zhu¹

45.

Combination Therapy for Non-Alcoholic Steatohepatitis: Rationale, Opportunities and Challenges

Gut. 2020 May 7;gutjnl-2019-319104. doi: 10.1136/gutjnl-2019-319104.Online ahead of print.

Jean-François Dufour^1 2, Cyrielle Caussy^3 4, Rohit Loomba⁵

46.

Review Article: The Emerging Role of Genetics in Precision Medicine for Patients With Non-Alcoholic Steatohepatitis

Aliment Pharmacol Ther. 2020 Jun;51(12):1305-1320. doi: 10.1111/apt.15738.Epub 2020 May 7.

Björn Carlsson¹, Daniel Lindén^1 2, Gabriella Brolén³, Mathias Liljeblad¹, Mikael Bjursell¹, Stefano Romeo^4 5 6, Rohit Loomba⁷

47.

Increased Atherogenic Lipoprotein Profile in Children With Non-Alcoholic Steatohepatitis

Pediatr Obes. 2020 May 4;e12648 doi: 10.1111/ijpo.12648. Online ahead of print.

Eduardo Castillo-Leon¹, Margery A Connelly², Juna V Konomi¹, Shelley Caltharp^3 4, Rebecca Cleeton¹, Miriam B Vos^1 4 5

48.

Nonalcoholic Fatty Liver Disease and Alcoholic Liver Disease Are Major Drivers of Liver Mortality in the United States

Hepatol Commun. 2020 Apr 4;4(6):890-903. doi: 10.1002/hep4.1510. eCollection 2020 Jun.

James M Paik¹, Pegah Golabi¹, Rakesh Biswas¹, Saleh Alqahtani², Chapy Venkatesan¹, Zobair M Younossi^1 3

49.

Low Thyroid Function in Nonalcoholic Fatty Liver Disease Is an Independent Predictor of All-Cause and Cardiovascular Mortality

Am J Gastroenterol. 2020 Jun 3. doi: 10.14309/ajg.0000000000000654. Online ahead of print.

Donghee Kim¹, Luis Miguel Vazquez-Montesino², Jessica A Escober¹, Christopher T Fernandes¹, George Cholankeril¹, Rohit Loomba^3 4, Stephen A Harrison^5 6, Zobair M Younossi⁷, Aijaz Ahmed¹

50.

Biopsy Rate and Nonalcoholic Steatohepatitis (NASH) in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

Scand J Gastroenterol. 2020 Jun 1;1-6. doi: 10.1080/00365521.2020.1766554.Online ahead of print.

Florian Gerhardt¹, David Petroff², Valentin Blank^1 3, Albrecht Böhlig¹, Florian van Bömmel¹, Christian Wittekind⁴, Thomas Berg¹, Thomas Karlas¹, Johannes Wiegand¹

51.

Standardization of Diet and Exercise in Clinical Trials of NAFLD-NASH: Recommendations From the Liver Forum

J Hepatol. 2020 Apr 27;S0168-8278(20)30274-9.doi: 10.1016/j.jhep.2020.04.030.Online ahead of print.

Oliver Glass¹, Claudia Filozof², Mazen Noureddin³, Mark Berner-Hansen⁴, Elmer Schabel⁵, Stephanie O Omokaro⁶, Jörn M Schattenberg⁷, Katherine Barradas⁸, Veronica Miller⁸, Sven Francque⁹, Manal F Abdelmalek¹⁰, Liver Forum Standard of Care Working Group

52.

Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial

Gastroenterol. 2020 May 15. doi: 10.14309/ajg.0000000000000661. Online ahead of print.

53.

Presence of Serum Antinuclear Antibodies Does Not Impact Long-Term Outcomes in Nonalcoholic Fatty Liver Disease

Gastroenterol. 2020 May 25. doi: 10.14309/ajg.0000000000000676. Online ahead of print.

Ramy Younes^1 2, Olivier Govaere², Salvatore Petta³, Luca Miele^4 5, Dina Tiniakos², Alastair Burt², Ezio David⁶, Fabio M Vecchio^4 7, Marco Maggioni⁸, Daniela Cabibi⁹, Anna L Fracanzani¹⁰, Chiara Rosso¹, Maria J Garcia Blanco¹¹, Angelo Armandi¹, Gian Paolo Caviglia¹, Marco Y W Zaki^2 12, Antonio Liguori⁴, Paolo Francione¹⁰, Grazia Pennisi³, Antonio Grieco^4 5, Luca Valenti¹³, Quentin M Anstee^2 14, Elisabetta Bugianesi¹

54.

Nonalcoholic Fatty Liver Disease Progression Rates to Cirrhosis and Progression of Cirrhosis to Decompensation and Mortality: A Real World Analysis of Medicare Data

Aliment Pharmacol Ther. 2020 Jun;51(11):1149-1159. doi: 10.1111/apt.15679. Epub 2020 May 5.

Rohit Loomba^1 2, Robert Wong³, Jeremy Fraysse⁴, Sanatan Shreay⁴, Suying Li⁵, Stephen Harrison⁶, Stuart C Gordon⁷

55.

Alanine Aminotransferase and Gamma Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis

Hepatology. 2020 May 16.doi: 10.1002/hep.31317. Online ahead of print.

Kimberly P Newton^1 2, Joel E Lavine³, Laura Wilson^4 5, Cynthia Behling^6 7, Miriam B Vos⁸, Jean P Molleston⁹, Philip Rosenthal¹⁰, Tamir Miloh¹¹, Mark H Fishbein¹², Ajay K Jain¹³, Karen F Murray¹⁴, Jeffrey B Schwimmer^1 2, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN):

Donna Garner, Paula Hertel, Ryan Himes, Alicia Lawson, Tamir Miloh, Nicole Triggs, Kristin Bramlage, April Carr, Kim Cecil, Meghan McNeill, Marialena Mouzaki, Andrew Trout, Stavra Xanthakos, Kimberlee Bernstein, Stephanie DeVore, Rohit Kohli, Kathleen Lake, Daniel Podberesky, Alex Towbin, Joel E Lavine, Ali Mencin, Elena Reynoso, Adina Alazraki, Rebecca Cleeton, Maria Cordero, Albert Hernandez, Saul Karpen, Jessica Cruz Munos, Nicholas Raviele, Miriam Vos, Molly Bozic, Laura Carr, Oscar W Cummings, Kathryn Harlow, Ann Klipsch, Jean P Molleston, Emily Ragozzino, Girish Rao, Kimberly Kafka, Ann Scheimann, Mark H Fishbein, Saeed Mohammad, Peter F Whitington, Sarah Barlow, Elizabeth M Brunt, Danielle Carpenter, Theresa Cattoor, Jose Derdoy, Janet Freebersyser, Ajay Jain Debra King, Jinping Lai, Joan Siegner, Susan Stewart, Susan Torretta, Kristina Wriston, Jennifer Arin, Cynthia Behling, Craig Bross, Carissa Carrier, Diana De La Pena, Janis Durelle, Mary Catherine Huckaby, Michael S Middleton, Kimberly Newton, Jeffrey B Schwimmer, Claude Sirlin, Patricia Ugalde-Nicalo, Jesse Courtier, Ryan Gill, Camille Langlois, Emily Rothbaum Perito, Philip Rosenthal, Patrika Tsai, Niviann Blondet, Kara Cooper, Karen Murray, Randolph Otto, Matthew Yeh, Melissa Young, Elizabeth M Brunt, Kathryn Fowler, David E Kleiner, Edward C Doo, Sherry Hall, Jay H Hoofnagle, Patricia R Robuck, Averell H Sherker, Rebecca Torrance, Patricia Belt, Jeanne M Clark, John Dodge, Michele Donithan, Milana Isaacson, Mariana Lazo, Jill Meinert, Laura Miriel, Emily P Sharkey, Jacqueline Smith, Michael Smith, Alice Sternberg, James Tonascia, Mark L Van Natta, Annette Wagoner, Laura A Wilson, Goro Yamada, Katherine P Yates

56.

Sexual Dimorphism of NAFLD in Adults. Focus on Clinical Aspects and Implications for Practice and Translational Research

Clin Med. 2020 Apr 28;9(5):E1278. doi: 10.3390/jcm9051278.

Amedeo Lonardo¹, Ayako Suzuki²

57.

Evolving Aspects of Liver Transplantation for Nonalcoholic Steatohepatitis

Curr Opin Organ Transplant. 2013 Jun;18(3):251-8.doi: 10.1097/MOT.0b013e3283615d30.

Michael Charlton¹

58.

Non-alcoholic Liver Disease and Childhood Obesity

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141.	Nonalcoholic Steatohepatitis Becomes the Leading Indication for Liver Transplant Registrants Among US Adults Born Between 1945 and 1965
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142.	Multiparametric Magnetic Resonance Elastography Improves the Detection of NASHRegression Following Bariatric Surgery
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Newsome PN¹, Sasso M², Deeks JJ³, Paredes A⁴, Boursier J⁵, Chan WK⁶, Yilmaz Y⁷, Czernichow S⁸, Zheng MH⁹, Wong VW¹⁰, Allison M¹¹, Tsochatzis E¹², Anstee QM¹³, Sheridan DA¹⁴, Eddowes PJ¹⁵, Guha IN¹⁵, Cobbold JF¹⁶, Paradis V¹⁷, Bedossa P¹⁸, Miette V², Fournier-Poizat C¹⁹, Sandrin L², Harrison SA²⁰. Lancet Gastroenterol Hepatol. 2020 Feb 3. pii: S2468-1253(19)30383-8. doi: 10.1016/S2468-1253(19)30383-8. [Epub ahead of print]

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145.	Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C
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146.	Proportion of NAFLD patients with normal ALT value in overall NAFLD patients: a systematic review and meta-analysis
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147.	Fibroblast growth factor (FGF)-21 based therapies: A magic bullet for nonalcoholic fatty liver disease (NAFLD)?
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150.	NASH (nonalcoholic steatohepatitis), diabetes, and macrovascular disease: multiple chronic conditions and a potential treatment at the metabolic root
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152.	Macrophage Function in the Pathogenesis of Non-alcoholic Fatty Liver Disease: The Mac Attack
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153.	Presumed Nonalcoholic Fatty Liver Disease Among Medicare Beneficiaries With HIV, 2006-2016
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154.	Efficacy and safety of anti-hyperglycaemic drugs in patients with non-alcoholic fatty liver disease with or without diabetes: An updated systematic review of randomized controlled trials
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156.	A Model to Identify Heavy Drinkers at High Risk for Liver Disease Progression
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158.	Continued muscle loss increases mortality in cirrhosis- impact of etiology of liver disease
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159.	Childhood and Adolescent Nonalcoholic Fatty Liver Disease: Is It Different from Adults?
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160.	Carotenoids and fatty liver disease: Current knowledge and research gaps
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161.	Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression
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163.	A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH
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164.	Evaluation of Dietary Approaches for the Treatment of Non-Alcoholic Fatty Liver Disease: A Systematic Review
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165.	Nonalcoholic Fatty Liver Disease and Fibrosis Associated With Increased Risk of Cardiovascular Events in a Prospective Study
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166.	When the Liver Gets Stiff, the Tough Get Moving
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167.	Nonalcoholic Fatty Liver Disease: An Emerging Driver of Hypertension
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168.	Derivation and Internal Validation of a Clinical Prediction Tool to Predict Nonalcoholic FattyLiver Disease in Patients With Crohn
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169.	Noninvasive assessment of hepatic steatosis and fibrosis in patients with severe obesity
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171.	Moderate Alcohol Intake in Non-Alcoholic Fatty Liver Disease: To Drink or Not to Drink?
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172.	Effects of alternate-day fasting on body weight and dyslipidaemia in patients with non-alcoholic fatty liver disease: a randomised controlled trial
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173.	Relationship between non-alcoholic fatty liver disease during pregnancy and abnormal glucose metabolism during and after pregnancy
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174.	Bariatric Surgery in Cirrhotic Patients: Is It Safe?
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175.	Nonalcoholic Fatty Liver Disease: A Challenge from Mechanisms to Therapy
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176.	Disease Severity Is Associated With Higher Healthcare Utilization in Nonalcoholic Steatohepatitis Medicare Patients
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177.	Insulin Resistance and Genetic Risk Predict Liver-Related Outcomes and Death in Nonalcoholic Fatty Liver Disease
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178.	Influence of lifestyle factors and staple foods from the Mediterranean diet on non-alcoholic fatty liver disease among older individuals with metabolic syndrome features
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179.	Association between neck circumference and non-alcoholic fatty liver disease in Mexican children and adolescents with obesity
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180.	A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver DiseaseAnd Non-Alcoholic Steatohepatitis
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181.	Mediterranean Diet and NAFLD: What We Know and Questions That Still Need to Be Answered
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182.	Higher Sodium Intake Assessed by 24 Hour Urinary Sodium Excretion Is Associated with Non-Alcoholic Fatty Liver Disease: The PREVEND Cohort Study
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183.	High Protein Diet and Metabolic Plasticity in Non-Alcoholic Fatty Liver Disease: Myths and Truths
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184.	A retrospective case control study identifies peripheral blood mononuclear cell albumin RNA expression as a biomarker for non-alcoholic fatty liver disease
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185.	Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis
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186.	Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development
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187.	REGENERATE: Design of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis
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188.	Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis
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Younossi ZM¹, Ratziu V², Loomba R³, Rinella M⁴, Anstee QM⁵, Goodman Z¹, Bedossa P⁶, Geier A⁷, Beckebaum S⁸, Newsome PN⁹, Sheridan D¹⁰, Sheikh MY¹¹, Trotter J¹², Knapple W¹³, Lawitz E¹⁴, Abdelmalek MF¹⁵, Kowdley KV¹⁶, Montano-Loza AJ¹⁷, Boursier J¹⁸, Mathurin P¹⁹, Bugianesi E²⁰, Mazzella G²¹, Olveira A²², Cortez-Pinto H²³, Graupera I²⁴, Orr D²⁵, Gluud LL²⁶, Dufour JF²⁷, Shapiro D²⁸, Campagna J²⁸, Zaru L²⁸, MacConell L²⁸, Shringarpure R²⁸, Harrison S²⁹, Sanyal AJ³⁰; REGENERATE Study Investigators.

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190.	Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes
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191.	The Role of Noninvasive Tests for Differentiating NASH From NAFL and Diagnosing Advanced Fibrosis Among Patients With NAFLD
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192.	Impact of NAFLD on the Incidence of Cardiovascular Diseases in a Primary Care Population in Germany
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193.	New drugs for NAFLD: lessons from basic models to the clinic
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194.	Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
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195.	A randomized, double-blind, multicenter, phase 2b study to evaluate the safety and efficacy of a combination of tropifexor and cenicriviroc in patients with nonalcoholic steatohepatitis and liver fibrosis: Study design of the TANDEM trial.
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498.	Vitamin E Improves Transplant-free Survival and Hepatic Decompensation among Patients with NASH and Advanced Fibrosis
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508.	Steatosis in Liver Transplantation: Current Limitations and Future Strategies
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510.	The Future of Nonalcoholic Fatty Liver Disease Treatment
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511.	Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase 3/7 activation in subjects with non-alcoholic fatty liver disease
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512.	Non-alcoholic fatty liver disease and colorectal cancer survival
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515.	Advances and challenges in the management of advanced fibrosis in nonalcoholic steatohepatitis
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516.	European paediatric non-alcoholic fatty liver disease registry (EU-PNAFLD): Design and rationale
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517.	Clinical workup of fatty liver for the primary care provider
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519.	Methods to improve the noninvasive diagnosis and assessment of disease severity in children with suspected nonalcoholic fatty liver disease (NAFLD): Study design
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520.	Nonalcoholic Fatty Liver Disease
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523.	Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis
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524.	BET Inhibition Improves NASH and Liver Fibrosis
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525.	Validation of Serum Test for Advanced Liver Fibrosis in Patients with Nonalcoholic Steatohepatitis
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526.	Management of Recurrent and De Novo NAFLD/NASH after Liver Transplantation
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528.	Causality between non-alcoholic fatty liver disease and risk of cardiovascular disease and type 2 diabetes: A meta-analysis with bias analysis
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532.	A Novel Regulatory Role of Apoptosis Antagonizing Transcription Factor in the Pathogenesis of NAFLD and HCC
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539.	Chronic Kidney Disease is Independently Associated with Increased Mortality in Patients with Non-alcoholic Fatty Liver Disease
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540.	Treatment of NASH with Gastric Bypass
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542.	The global prevalence and genetic spectrum of lysosomal acid lipase deficiency: a rare condition that mimics NAFLD
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549.	Predictors of Nonalcoholic Steatohepatitis and Significant Fibrosis in Non-Obese Nonalcoholic Fatty Liver Disease
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551.	Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease
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552.	Among Patients With NAFLD, Treatment of Dyslipidemia Does Not Reduce Cardiovascular Mortality
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553.	NASH: The Emerging Most Common Form of Chronic Liver Disease
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554.	Ultrasonographic Nonalcoholic Fatty Pancreas Is Associated with Advanced Fibrosis in NAFLD: A Retrospective Analysis
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556.	Effect of Body Mass Index, Metabolic Health and Adipose Tissue Inflammation on the Severity of Non-alcoholic Fatty Liver Disease in Bariatric Surgical Patients: a Prospective Study
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558.	When to Initiate Weight Loss Medications in the NAFLD Population
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559.	Obesity and nonalcoholic fatty liver disease: current perspectives
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560.	Nonalcoholic Liver Disease in Children and Adolescents
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561.	Factors Associated with Histologic Response in Adult Patients with Nonalcoholic Steatohepatitis
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562.	An exploratory study examining how nano-liquid chromatography-mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease
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563.	Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease
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564.	Overview of Updated Practice Guidelines for Pediatric Nonalcoholic Fatty Liver Disease
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565.	C-peptide as a key risk factor for non-alcoholic fatty liver disease in the United States population
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566.	Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial
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567.	Burden of Illness and Economic Model for Patients with Non-Alcoholic Steatohepatitis (NASH) in the United States
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569.	Current guidelines for the management of non-alcoholic fatty liver disease: A systematic review with comparative analysis
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570.	Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease
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572.	Different roles of FAT10, FOXO1, and ADRA2A in hepatocellular carcinoma tumorigenesis in patients with alcoholic steatohepatitis (ASH) vs non-alcoholic steatohepatitis (NASH)
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573.	Unmet needs in pediatric NAFLD research: what do we need to prioritize for the future?
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578.	Global Perspectives on Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis
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585.	Ad libitum Mediterranean or low fat diets as treatments for non-alcoholic fatty liver disease?
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587.	Cognitive Performance in Individuals With NonAlcoholic Fatty Liver Disease and/or Type 2 Diabetes Mellitus
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591.	Nonalcoholic steatohepatitis, obesity, and cardiac dysfunction
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597.	Association Between Magnetic Resonance Imaging-Proton Density Fat Fraction and LiverHistology Features in Patients With Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis
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600.	Changing Trends in Etiology-based Annual Mortality From Chronic Liver Disease, From 2007 Through 2016
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601.	Effects of dapagliflozin and n-3 carboxylic acids on non-alcoholic fatty liver disease in people with type 2 diabetes: a double-blind randomised placebo-controlled study
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602.	Rates and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis
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603.	Macrophages in Nonalcoholic Steatohepatitis: Friend or Foe?
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604.	Mechanisms of NAFLD development and therapeutic strategies
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605.	Non-alcoholic Fatty Liver Disease: A Review of Anti-diabetic Pharmacologic Therapies
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606.	Adiposity and gastrointestinal cancers: epidemiology, mechanisms and future directions
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607.	A Case-control Study to Evaluate the Prevalence of Nonalcoholic Fatty Liver Disease Among Patients with Moderate-to-severe Psoriasis
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608.	The characterisation of hepatic mitochondrial function in patients with non-alcoholic fatty liver disease (NAFLD) using the 13C-ketoisocaproate breath test
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609.	Recent advances in understanding and managing non-alcoholic fatty liver disease
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610.	Inadequate Hepatocellular Carcinoma Screening in Patients With Nonalcoholic Steatohepatitis Cirrhosis
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611.	Non-alcoholic Steatohepatitis is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates
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612.	Emricasan Improves Liver Function in Patients With Cirrhosis and High Model for End-stage Liver Disease Scores Compared With Placebo
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613.	Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
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614.	Lifestyle intervention for morbid obesity: effects on liver steatosis, inflammation and fibrosis
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615.	Pediatric Nonalcoholic Fatty Liver Disease in New York City: An Autopsy Study
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616.	The nonalcoholic fatty liver disease (NAFLD) fibrosis score, cardiovascular risk stratification and a strategy for secondary prevention with ezetimibe
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617.	Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial
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618.	Rates and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis
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619.	NASH in Nondiabetic Endocrine Disorders
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620.	Nonalcoholic fatty liver disease remission in men through regular exercise
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621.	Nonalcoholic fatty liver disease with elevated alanine aminotransferase levels is negatively associated with bone mineral density: Cross-sectional study in U.S. adults
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622.	Type and Pattern of Alcohol Consumption is Associated With Liver Fibrosis in Patients With Non-alcoholic Fatty Liver Disease
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623.	NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances
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624.	Lifestyle intervention for morbid obesity: effects on liver steatosis, inflammation and fibrosis
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625.	Non-alcoholic fatty liver disease severity and metabolic complications in obese children: impact of omega-3 fatty acids
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626.	Omega-3 Fatty Acids and Fatty Liver Disease in Children
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627.	Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease
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628.	Hepatic artery resistive index as surrogate marker for fibrosis progression in NAFLD patients: A clinical perspective
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630.	Physical deconditioning is the common denominator in both obese and overweight subjects with nonalcoholic steatohepatitis
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635.	Gender Disparities in Liver Transplant Candidates with Non-Alcoholic Steatohepatitis
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666.	Fatty liver index is associated to pulse wave velocity in healthy subjects: Data from the Brisighella Heart Study
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682.	Nonalcoholic Fatty Liver Disease in Children
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