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The summaries are free for public use. The Chronic Liver Disease Foundation will continue to add and archive summaries of articles deemed relevant to CLDF by the Board of Trustees and its Advisors.
  1. Quality of life in patients with minimal hepatic encephalopathy
    Ridola L1, Nardelli S2, Gioia S2, Riggio O2. World J Gastroenterol. 2018 Dec 28;24(48):5446-5453. doi: 10.3748/wjg.v24.i48.5446.


  2. Hepatic encephalopathy 2018: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF)
    Montagnese S1, Russo FP2, Amodio P3, Burra P2, Gasbarrini A4, Loguercio C5, Marchesini G6, Merli M7, Ponziani FR4, Riggio O7, Scarpignato C8. Dig Liver Dis. 2018 Dec 12. pii: S1590-8658(18)31274-X. doi: 10.1016/j.dld.2018.11.035. [Epub ahead of print]


  3. Clinical Predictors for Poor Quality of Life in Patients With Covert Hepatic Encephalopathy
    Labenz C1,2, Toenges G3, Schattenberg JM1,2, Nagel M1,2, Sprinzl MF1,2, Nguyen-Tat M1,2, Zimmermann T1,2, Huber Y1,2, Marquardt JU1,2, Galle PR1,2, Wörns MA1,2. J Clin Gastroenterol. 2018 Nov 14. doi: 10.1097/MCG.0000000000001149. [Epub ahead of print]


  4. MHE Testing in Real World Scenario
    Lauridsen MM1, Vilstrup H2. J Clin Exp Hepatol. 2018 Dec;8(4):438-440. doi: 10.1016/j.jceh.2018.04.010. Epub 2018 May 5.


  5. Current Diagnosis and Classification of Hepatic Encephalopathy
    Amodio P1. J Clin Exp Hepatol. 2018 Dec;8(4):432-437. doi: 10.1016/j.jceh.2018.07.001. Epub 2018 Jul 11.


  6. The role of Branched Chain Amino Acids in the treatment of hepatic Encephalopathy
    Dam G1, Aamann L1, Vistrup H1, Gluud LL2. J Clin Exp Hepatol. 2018 Dec;8(4):448-451. doi: 10.1016/j.jceh.2018.06.004. Epub 2018 Jun 27.


  7. Diet and the Role of Food in Common Gastrointestinal Diseases
    Pearlman M1, Akpotaire O2. Med Clin North Am. 2019 Jan;103(1):101-110. doi: 10.1016/j.mcna.2018.08.008.


  8. Long-term management of hepatic encephalopathy with lactulose and/or rifaximin: a review of the evidence
    Hudson M1,2, Schuchmann M3. Eur J Gastroenterol Hepatol. 2018 Nov 15. doi: 10.1097/MEG.0000000000001311. [Epub ahead of print]


  9. Diagnosis of covert hepatic encephalopathy: a multi-center study testing the utility of single versus combined testing
    Duarte-Rojo A1, Allampati S2, Thacker LR3, Flud CR1, Patidar KR4, White MB4, Klair JS1, Heuman DM4, Wade JB5, Gavis EA4, Bajaj JS6. Metab Brain Dis. 2018 Nov 30. doi: 10.1007/s11011-018-0350-z. [Epub ahead of print]


  10. Valproic acid induced acute liver injury resulting in hepatic encephalopathy- a case report and literature review
    Gayam V1, Mandal AK1, Khalid M1, Shrestha B1, Garlapati P1, Khalid M2. J Community Hosp Intern Med Perspect. 2018 Oct 15;8(5):311-314. doi: 10.1080/20009666.2018.1514933. eCollection 2018.


  11. Treatment with proton pump inhibitors increases the risk for development of hepatic encephalopathy after implantation of transjugular intrahepatic portosystemic shunt (TIPS)
    Sturm L1, Bettinger D1,2, Giesler M1, Boettler T1, Schmidt A1, Buettner N1, Thimme R1, Schultheiss M1. United European Gastroenterol J. 2018 Nov;6(9):1380-1390. doi: 10.1177/2050640618795928. Epub 2018 Aug 15.


  12. Hepatic encephalopathy: Sometimes more portal than hepatic
    Aller MA1, Arias N2,3, Blanco-Rivero J4, Arias JL3,5, Arias J1. J Gastroenterol Hepatol. 2018 Oct 21. doi: 10.1111/jgh.14514. [Epub ahead of print]


  13. Frailty, Psychoactive Medications, and Cognitive Dysfunction are Associated with Poor Patient-Reported Outcomes in Cirrhosis
    Tapper EB1, Baki J1, Parikh ND1, Lok AS1. Hepatology. 2018 Nov 1. doi: 10.1002/hep.30336. [Epub ahead of print]


  14. Effects of branched chain amino acid supplementation on patient care outcomes in adults and children with liver cirrhosis: A systematic review
    Ooi PH1, Gilmour SM2, Yap J2, Mager DR3. Clin Nutr ESPEN. 2018 Dec;28:41-51. doi: 10.1016/j.clnesp.2018.07.012. Epub 2018 Aug 14.


  15. Efficacy of l-Ornithine l-Aspartate for the Treatment of Hepatic Encephalopathy and Hyperammonemia in Cirrhosis: Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Butterworth RF1, Kircheis G2, Hilger N3, McPhail MJW4. J Clin Exp Hepatol. 2018 Sep;8(3):301-313. doi: 10.1016/j.jceh.2018.05.004. Epub 2018 May 22.


  16. Hyperammonemia in Hepatic Encephalopathy
    Jayakumar AR1,2, Norenberg MD3,4,5. J Clin Exp Hepatol. 2018 Sep;8(3):272-280. doi: 10.1016/j.jceh.2018.06.007. Epub 2018 Jun 20.


  17. Periodontal Therapy Favorably Modulates the Oral-Gut-Hepatic Axis in Cirrhosis
    Bajaj JS1, Matin P2, White MB, Fagan A3, Golob Deeb J4, Acharya C5, Dalmet SS6, Sikaroodi M7, Gillevet PM7, Sahingur SE8. Am J Physiol Gastrointest Liver Physiol. 2018 Aug 17. doi: 10.1152/ajpgi.00230.2018. [Epub ahead of print]


  18. EASL Clinical Practice Guidelines on nutrition in chronic liver disease
    Merli M, Berzigotti A, Zelber-Sagi S, Dasarathy S, Montagnese S, Genton L, Plauth M, Parés A. J Hepatol. 2018 Aug 22. pii: S0168-8278(18)32177-9. doi: 10.1016/j.jhep.2018.06.024. [Epub ahead of print]


  19. Cerebral Blood Flow and Metabolism in Hepatic Encephalopathy-A Meta-Analysis
    Bjerring PN1,2, Gluud LL2, Larsen FS1. J Clin Exp Hepatol. 2018 Sep;8(3):286-293. doi: 10.1016/j.jceh.2018.06.002. Epub 2018 Jun 20.


  20. Pathogenesis of Hepatic Encephalopathy in Chronic Liver Disease
    Ochoa-Sanchez R1, Rose CF1. J Clin Exp Hepatol. 2018 Sep;8(3):262-271. doi: 10.1016/j.jceh.2018.08.001. Epub 2018 Aug 18.


  21. Race and Gradient Difference Are Associated with Increased Risk of Hepatic EncephalopathyHospital Admission After Transjugular Intrahepatic Portosystemic Shunt Placement
    Rowley MW1,2, Choi M3, Chen S4,2, Hirsch K4,2, Seetharam AB5,2. J Clin Exp Hepatol. 2018 Sep;8(3):256-261. doi: 10.1016/j.jceh.2017.12.003. Epub 2017 Dec 30.


  22. Design of the Prospective Real-world Outcomes Study of hepatic encephalopathy Patients' Experience on Rifaximin-? (PROSPER): an observational study among 550 patients
    Krag A1, Schuchmann M2, Sodatonou H3, Pilot J3, Whitehouse J4, Strasser SI5, Hudson M6. Hepatol Med Policy. 2018 Jan 8;3:4. doi: 10.1186/s41124-017-0029-9. eCollection 2018.


  23. Proton pump inhibitors are associated to minimal and overt hepatic encephalopathy and increase mortality in cirrhotics.
    Nardelli S1, Gioia S1, Ridola L1, Farcomeni A1,2, Merli M1, Riggio O1. Hepatology. 2018 Oct 5. doi: 10.1002/hep.30304. [Epub ahead of print]


  24. Rifaximin has the potential to prevent complications of cirrhosis
    Flamm SL1, Mullen KD2, Heimanson Z3, Sanyal AJ4. Therap Adv Gastroenterol. 2018 Sep 28;11:1756284818800307. doi: 10.1177/1756284818800307. eCollection 2018.


  25. Complications of Cirrhosis in Primary Care: Recognition and Management of Hepatic Encephalopathy
    Flamm SL1. Am J Med Sci. 2018 Sep;356(3):296-303. doi: 10.1016/j.amjms.2018.06.008. Epub 2018 Jun 19.


  26. Olfactory Function is Affected in Patients with Cirrhosis Depending on the Severity of Hepatic Encephalopathy
    Heiser C1, Haller B2, Sohn M3, Hofauer B1, Knopf A2, Mühling T4, Freiherr J5, Bender M4, Tiller M4, Schmidt A4, Schepp W4, Gundling F. Ann Hepatol. 2018 Aug 24;17(5):822-829. doi: 10.5604/01.3001.0012.3143.


  27. Hepatic encephalopathy impacts the predictive value of the Fried Frailty Index
    Tapper EB1,2, Konerman M1, Murphy S3,4, Sonnenday CJ5. Am J Transplant. 2018 Jul 18. doi: 10.1111/ajt.15020. [Epub ahead of print]


  28. Evaluation of the cost-effectiveness of rifaximin-? for the management of patients with hepatic encephalopathy in the United Kingdom
    Berni E1, Murphy D2, Whitehouse J2, Conway P1, Di Maggio P2, Currie CJ1,3, Poole C4. Curr Med Res Opin. 2018 Aug 13:1-8. doi: 10.1080/03007995.2018.1499506. [Epub ahead of print]


  29. Current Management of Hepatic Encephalopathy
    Acharya C1, Bajaj JS2. Am J Gastroenterol. 2018 Jul 13. doi: 10.1038/s41395-018-0179-4. [Epub ahead of print]


  30. Systematic Review of the Economic Burden of Overt Hepatic Encephalopathy and Pharmacoeconomic Impact of Rifaximin
    Neff G1, Zachry W 3rd2. Pharmacoeconomics. 2018 Jul;36(7):809-822. doi: 10.1007/s40273-018-0641-6.


  31. Coil-Assisted Retrograde Transvenous Obliteration (CARTO): An Alternative Treatment Option for Refractory Hepatic Encephalopathy
    Lee EW1,2, Saab S, Kaldas F3,4, Fletcher S5, Busuttil RW3,4, Durazo F3,6, McWilliams JP5, DiNorcia J 3rd3,4, Padia SA5, Kee ST5. Am J Gastroenterol. 2018 Aug;113(8):1187-1196. doi: 10.1038/s41395-018-0109-5. Epub 2018 Jun 14.


  32. Hepatic encephalopathy: current challenges and future prospects
    Swaminathan M1, Ellul MA2, Cross TJ1. Hepat Med. 2018 Mar 22;10:1-11. doi: 10.2147/HMER.S118964. eCollection 2018.


  33. Why and when to measure ammonemia in cirrhosis?
    Mallet M1, Weiss N2, Thabut D1, Rudler M3. Clin Res Hepatol Gastroenterol. 2018 Mar 15. pii: S2210-7401(18)30031-7. doi: 10.1016/j.clinre.2018.01.004. [Epub ahead of print]


  34. Refractory Hepatic Encephalopathy After Elective Transjugular Intrahepatic Portosystemic Shunt: Risk Factors and Outcomes with Revision
    Rowley MW1,2, Choi M3, Chen S4,2, Hirsch K4,2, Seetharam AB5,6. Cardiovasc Intervent Radiol. 2018 Jun 5. doi: 10.1007/s00270-018-1992-2. [Epub ahead of print]


  35. Patient Acceptance of Lactulose Varies Between Indian and American Cohorts: Implications for Comparing and Designing Global Hepatic Encephalopathy Trials
    Rathi S1, Fagan A2, Wade JB3, Chopra M1, White MB2, Ganapathy D2, Acharya C2, Dhiman RK1, Bajaj JS2. J Clin Exp Hepatol. 2018 Jun;8(2):109-115. doi: 10.1016/j.jceh.2017.11.010. Epub 2017 Dec 2.


  36. New concepts on intestinal microbiota and the role of the non-absorbable antibiotics with special reference to rifaximin in digestive diseases
    Bajaj JS1, Barbara G2, DuPont HL3, Mearin F4, Gasbarrini A5, Tack J6. Dig Liver Dis. 2018 Aug;50(8):741-749. doi: 10.1016/j.dld.2018.04.020. Epub 2018 Apr 27.


  37. Liver-Microbiome Axis in Health and Disease
    Adolph TE1, Grander C1, Moschen AR1, Tilg H2.


  38. Diagnosis of Minimal Hepatic Encephalopathy: A Systematic Review of Point-of-Care Diagnostic Tests
    Tapper EB1,2,3, Parikh ND1,2,3, Waljee AK1,2,3, Volk M4, Carlozzi NE5, Lok AS1,2. Am J Gastroenterol. 2018 Apr;113(4):529-538. doi: 10.1038/ajg.2018.6. Epub 2018 Mar 13.


  39. Considerations for the cost-effective management of hepatic encephalopathy
    Flamm SL1. Am J Manag Care. 2018 Mar;24(4 Suppl):S51-S61.


  40. Management of Hepatic Encephalopathy Not Responsive to First-Line Treatments
    Nardelli S1, Ridola L2, Gioia S3, Riggio O3. Curr Treat Options Gastroenterol. 2018 Jun;16(2):253-259. doi: 10.1007/s11938-018-0183-1.


  41. Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis is Restored by Fecal Transplant
    Bajaj JS1, Kakiyama G1, Savidge T2, Takei H3, Kassam ZA4, Fagan A1, Gavis EA1, Pandak WM1, Nittono H3, Hylemon PB1, Boonma P2, Haag A2, Heuman DM1, Fuchs M1, John B1, Sikaroodi M5, Gillevet PM5. Hepatology. 2018 Apr 17. doi: 10.1002/hep.30037. [Epub ahead of print]


  42. Acute-on-Chronic Liver Failure: Getting ready for prime-time
    Bajaj JS1, Moreau R2, Kamath PS3, Vargas HE4, Arroyo V5, Reddy KR6, Szabo G7, Tandon P8, Olson J9, Karvellas C8, Gustot T10, Lai JC11, Wong F12. Hepatology. 2018 Apr 24. doi: 10.1002/hep.30056. [Epub ahead of print]


  43. Probiotics in Gastroenterology: How Pro Is the Evidence in Adults?
    Koretz RL1,2. Am J Gastroenterol. 2018 Jun 19. doi: 10.1038/s41395-018-0138-0. [Epub ahead of print]


  44. Coil-Assisted Retrograde Transvenous Obliteration (CARTO): An Alternative Treatment Option for Refractory Hepatic Encephalopathy
    Lee EW1,2, Saab S, Kaldas F3,4, Fletcher S5, Busuttil RW3,4, Durazo F3,6, McWilliams JP5, DiNorcia J 3rd3,4, Padia SA5, Kee ST5. Am J Gastroenterol. 2018 Jun 14. doi: 10.1038/s41395-018-0109-5. [Epub ahead of print]


  45. Critical flicker frequency test predicts overt hepatic encephalopathy and survival in patients with liver cirrhosis
    Barone M1, Shahini E1, Iannone A1, Viggiani MT1, Corvace V2, Principi M1, Di Leo A3. Dig Liver Dis. 2018 May;50(5):496-500. doi: 10.1016/j.dld.2018.01.133. Epub 2018 Jan 31.


  46. Refractory Hepatic Encephalopathy After Elective Transjugular Intrahepatic Portosystemic Shunt: Risk Factors and Outcomes with Revision
    Rowley MW1,2, Choi M3, Chen S4,2, Hirsch K4,2, Seetharam AB5,6. Cardiovasc Intervent Radiol. 2018 Jun 5. doi: 10.1007/s00270-018-1992-2. [Epub ahead of print]


  47. New concepts on intestinal microbiota and the role of the non-absorbable antibiotics with special reference to rifaximin in digestive diseases
    Bajaj JS1, Barbara G2, DuPont HL3, Mearin F4, Gasbarrini A5, Tack J6. Dig Liver Dis. 2018 Apr 27. pii: S1590-8658(18)30717-5. doi: 10.1016/j.dld.2018.04.020. [Epub ahead of print]


  48. L-ornithine L-aspartate for prevention and treatment of hepatic encephalopathyin people with cirrhosis
    Goh ET1, Stokes CS, Sidhu SS, Vilstrup H, Gluud LL, Morgan MY. Cochrane Database Syst Rev. 2018 May 15;5:CD012410. doi: 10.1002/14651858.CD012410.pub2.


  49. Acute-on-Chronic Liver Failure: Getting ready for prime-time
    Bajaj JS1, Moreau R2, Kamath PS3, Vargas HE4, Arroyo V5, Reddy KR6, Szabo G7, Tandon P8, Olson J9, Karvellas C8, Gustot T10, Lai JC11, Wong F12. Hepatology. 2018 Apr 24. doi: 10.1002/hep.30056. [Epub ahead of print]


  50. Development of a novel clinical staging model for cirrhosis using the Nationwide Inpatient Sample
    Haj M1, Hart M1, Rockey DC1. J Investig Med. 2018 May 14. pii: jim-2018-000709. doi: 10.1136/jim-2018-000709. [Epub ahead of print]


  51. Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis is Restored by Fecal Transplant
    Bajaj JS1, Kakiyama G1, Savidge T2, Takei H3, Kassam ZA4, Fagan A1, Gavis EA1, Pandak WM1, Nittono H3, Hylemon PB1, Boonma P2, Haag A2, Heuman DM1, Fuchs M1, John B1, Sikaroodi M5, Gillevet PM5. Hepatology. 2018 Apr 17. doi: 10.1002/hep.30037. [Epub ahead of print]


  52. Management of Hepatic Encephalopathy Not Responsive to First-Line Treatments
    Nardelli S1, Ridola L2, Gioia S3, Riggio O3. Curr Treat Options Gastroenterol. 2018 Jun;16(2):253-259. doi: 10.1007/s11938-018-0183-1.


  53. Hepatic encephalopathy: Diagnosis and management
    Amodio P1. Liver Int. 2018 Apr 6. doi: 10.1111/liv.13752. [Epub ahead of print]


  54. Covert hepatic encephalopathy leads to distinct alterations in the emotional state, independently of MELD-Score
    Greinert R#, Ripoll C, Zipprich A#.Z Gastroenterol. 2018 Jan 16. doi: 10.1055/s-0043-123766. [Epub ahead of print]


  55. Waitlist Outcomes in Liver Transplant Candidates with High MELD and Severe Hepatic Encephalopathy
    Gadiparthi C1, Cholankeril G2, Yoo ER3, Hu M4, Wong RJ5, Ahmed A6,7. Dig Dis Sci. 2018 Apr 2. doi: 10.1007/s10620-018-5032-5. [Epub ahead of print]


  56. Hepatic encephalopathy: current challenges and future prospects
    Swaminathan M1, Ellul MA2, Cross TJ1. Hepat Med. 2018 Mar 22;10:1-11. doi: 10.2147/HMER.S118964. eCollection 2018.


  57. Diagnosis of Minimal Hepatic Encephalopathy: A Systematic Review of Point-of-Care Diagnostic Tests
    Tapper EB1,2,3, Parikh ND1,2,3, Waljee AK1,2,3, Volk M4, Carlozzi NE5, Lok AS1,2. Am J Gastroenterol. 2018 Mar 13. doi: 10.1038/ajg.2018.6. [Epub ahead of print]


  58. Why and when to measure ammonemia in cirrhosis?
    Mallet M1, Weiss N2, Thabut D1, Rudler M3. Clin Res Hepatol Gastroenterol. 2018 Mar 15. pii: S2210-7401(18)30031-7. doi: 10.1016/j.clinre.2018.01.004. [Epub ahead of print]


  59. Prevalence of restless legs syndrome in a tertiary cohort of ambulant patients with chronic liver disease
    Ma MX1, Huang Y1,2, Adams LA1,2, Gilpin R1, Garas G1,2, MacQuillan G1,2, Jeffrey GP1,2, Nicholas RM1. Intern Med J. 2018 Mar;48(3):347-350. doi: 10.1111/imj.13719.


  60. Interventions to improve physical function and prevent adverse events in cirrhosis
    Trivedi HD1, Tapper EB2. Gastroenterol Rep (Oxf). 2018 Feb;6(1):13-20. doi: 10.1093/gastro/gox042. Epub 2018 Jan 10.


  61. Gut?:?liver?:?brain axis: the microbial challenge in the hepatic encephalopathy
    Mancini A1, Campagna F2, Amodio P2, Tuohy KM1. Food Funct. 2018 Feb 27. doi: 10.1039/c7fo01528c. [Epub ahead of print]


  62. The burden of minimal hepatic encephalopathy: from diagnosis to therapeutic strategies
    Ridola L1, Cardinale V1, Riggio O2. Ann Gastroenterol. 2018 Mar-Apr;31(2):151-164. doi: 10.20524/aog.2018.0232. Epub 2018 Feb 1.


  63. Considerations for the cost-effective management of hepatic encephalopathy
    Flamm SL1. Am J Manag Care. 2018 Mar;24(4 Suppl):S51-S61.


  64. Assessment of the Spectrum of Hepatic Encephalopathy: A Multi-Center Study
    Reuter B1, Walter K2, Bissonnette J3, Leise MD4, Lai J5, Tandon P6, Kamath PS4, Biggins SW2, Rose CF3, Wade JB1, Bajaj JS1. Liver Transpl. 2018 Feb 19. doi: 10.1002/lt.25032. [Epub ahead of print]


  65. Reducing recurrent hospital admissions in patients with decompensated cirrhosis
    Aspinall RJ1. Br J Hosp Med (Lond). 2018 Feb 2;79(2):93-96. doi: 10.12968/hmed.2018.79.2.93.


  66. Effect of probiotic treatment on cirrhotic patients with minimal hepatic encephalopathy: A meta-analysis
    Cao Q1, Yu CB1, Yang SG1, Cao HC1, Chen P1, Deng M1, Li LJ2. Hepatobiliary Pancreat Dis Int. 2018 Feb;17(1):9-16. doi: 10.1016/j.hbpd.2018.01.005. Epub 2018 Feb 2.


  67. Effects of Alcohol on the Brain in Cirrhosis: Beyond Hepatic Encephalopathy
    Davis BC1, Bajaj JS1. Alcohol Clin Exp Res. 2018 Feb 8. doi: 10.1111/acer.13605. [Epub ahead of print]


  68. Breakthrough Clostridium difficile infection in cirrhotic patients receiving rifaximin
    Reigadas E1,2,3, Alcalá L1,3,4, Gómez J1, Marín M1,2,3,4, Martin A1,3, Onori R1, Muñoz P1,2,3,4, Bouza E1,2,3,4. Clin Infect Dis. 2017 Oct 23. doi: 10.1093/cid/cix918. [Epub ahead of print]


  69. Under-dilated TIPS Associate With Efficacy and Reduced Encephalopathy in a Prospective, Non-randomized Study of Patients With Cirrhosis
    Schepis F1, Vizzutti F2, Garcia-Tsao G3, Marzocchi G4, Rega L5, De Maria N6, Di Maira T6, Gitto S6, Caporali C4, Colopi S4, De Santis M4, Arena U7, Rampoldi A8, Airoldi A9, Cannavale A10, Fanelli F10, Mosconi C11, Renzulli M11, Agazzi R12, Nani R12, Quaretti P13, Fiorina I13, Moramarco L13, Miraglia R14, Luca A14, Bruno R15, Fagiuoli S16, Golfieri R11, Torricelli P4, Di Benedetto F17, Saverio Belli L9, Banchelli F18, Laffi G7, Marra F19, Villa E6. Clin Gastroenterol Hepatol. 2018 Jan 25. pii: S1542-3565(18)30097-1. doi: 10.1016/j.cgh.2018.01.029. [Epub ahead of print]


  70. Effect of Post-Traumatic Stress Disorder on Cognitive Function and Covert Hepatic Encephalopathy Diagnosis in Cirrhotic Veterans
    Burroughs TK1, Wade JB2, Ellwood MS1, Fagan A3, Heuman DM3, Fuchs M3, Bajaj JS4. Dig Dis Sci. 2018 Jan 8. doi: 10.1007/s10620-017-4894-2. [Epub ahead of print]


  71. Lactulose: A Simple Sugar in a Complex Encephalopathy
    Wijdicks EFM1. Neurocrit Care. 2018 Jan 2. doi: 10.1007/s12028-017-0494-4. [Epub ahead of print]


  72. The emergency medicine evaluation and management of the patient with cirrhosis
    Long B1, Koyfman A2. Am J Emerg Med. 2017 Dec 23. pii: S0735-6757(17)31049-5. doi: 10.1016/j.ajem.2017.12.047. [Epub ahead of print]


  73. Treating hepatic encephalopathy in cirrhotic patients admitted to ICU with sodium phenylbutyrate: a preliminary study
    Weiss N1,2,3,4,5,6,7,8, Tripon S1,2,3,4,5,6,7,8, Lodey M, Guiller E, Junot H, Monneret D1,2,3,4,5,6,7,8, Mayaux J, Brisson H, Mallet M1,2,3,4,5,6,7,8, Rudler M1,2,3,4,5,6,7,8, Imbert-Bismut F1,2,3,4,5,6,7,8, Thabut D1,4; Brain-Liver Pitié-Salpêtrière Study Group (BLIPS). Fundam Clin Pharmacol. 2017 Dec 14. doi: 10.1111/fcp.12340. [Epub ahead of print]


  74. Economic impact of the use of rifaximin 550 mg twice daily for the treatment of overt hepatic encephalopathy in Italy
    Roggeri DP1, Roggeri A1. Hepat Med. 2017 Sep 25;9:37-43. doi: 10.2147/HMER.S146438. eCollection 2017.


  75. A Risk Score to Predict the Development of Hepatic Encephalopathy in a Population-Based Cohort of Patients with Cirrhosis
    Tapper EB1,2, Parikh N1,2, Sengupta N3, Mellinger J1, Ratz D4, Lok AS1, Su GL1,2. Hepatology. 2017 Nov 1. doi: 10.1002/hep.29628. [Epub ahead of print]


  76. The impact of rifaximin-? on the hospital resource use associated with the management of patients with hepatic encephalopathy: a retrospective observational study (IMPRESS)
    Hudson M1, Radwan A2, Di Maggio P2, Cipelli R3, Ryder SD4, Dillon JF5, Cash WJ6, Przemioslo RT7, Wright M8, Shawcross DL9, Jalan R10, Saksena S11, Allison M12, Richardson P13, Farrington E14, Aspinall RJ15. Frontline Gastroenterol. 2017 Oct;8(4):243-251. doi: 10.1136/flgastro-2016-100792. Epub 2017 Apr 7.


  77. Recent advances in hepatic encephalopathy
    Liere V#1, Sandhu G#2, DeMorrow S1,3. F1000Res. 2017 Sep 4;6:1637. doi: 10.12688/f1000research.11938.1. eCollection 2017.


  78. An educational tool for the prophylaxis of hepatic encephalopathy
    Garrido M1, Turco M1, Formentin C1, Corrias M1, De Rui M1, Montagnese S1, Amodio P1. BMJ Open Gastroenterol. 2017 Sep 11;4(1):e000161. doi: 10.1136/bmjgast-2017-000161. eCollection 2017.


  79. Lactulose enemas in the treatment of hepatic encephalopathy. Do we help or harm?
    de Lorenzo-Pinto A1, García-Sánchez R2, Lorenzo-Salinas A3. Rev Esp Enferm Dig. 2017 Sep 18;109. doi: 10.17235/reed.2017.5106/2017. [Epub ahead of print]


  80. A pilot evaluation of a computer-based psychometric test battery designed to detect impairment in patients with cirrhosis
    Cook NA1, Kim JU1, Pasha Y1, Crossey MM1, Schembri AJ2,3, Harel BT2,4, Kimhofer T5, Taylor-Robinson SD1. Int J Gen Med. 2017 Sep 6;10:281-289. doi: 10.2147/IJGM.S140197. eCollection 2017.


  81. Brain Microstructural Abnormalities in Patients With Cirrhosis Without Overt Hepatic Encephalopathy: A Voxel-Based Diffusion Kurtosis Imaging Study
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    Lopes PJ, Mei MF, Guardia AC, Stucchi RS, Udo EY, Warwar MI, Boin IF. Transplant Proc. 2013 Apr;45(3):1122-5. doi: 10.1016/j.transproceed.2013.02.011.


  258. Impaired brain activity in cirrhotic patients with minimal hepatic encephalopathy: evaluation by near infrared spectroscopy
    Nakanishi H, Kurosaki M, Nakanishi K, Tsuchiya K, Noda T, Tamaki N, Yasui Y, Hosokawa T, Ueda K, Itakura J, Anami K, Asahina Y, Enomoto N, Higuchi T, Izumi N. Hepatol Res. 2013 Apr 5. doi: 10.1111/hepr.12127. [Epub ahead of print]


  259. GABAergic transmission in hepatic encephalopathy
    Sergeeva OA. Arch Biochem Biophys. 2013 Apr 23. pii: S0003-9861(13)00118-5. doi: 10.1016/j.abb.2013.04.005. [Epub ahead of print]


  260. Inflammation and Hepatic Encephalopathy
    Coltart I, Tranah TH, Shawcross DL. Arch Biochem Biophys. 2013 Apr 10. pii: S0003-9861(13)00105-7. doi: 10.1016/j.abb.2013.03.016. [Epub ahead of print]


  261. Cognitive functions in patients with liver cirrhosis: A tendency to commit more memory errors
    Cie?ko-Michalska I, Wójcik J, Senderecka M, Wyczesany M, Binder M, Szewczyk J, Dziedzic T, S?owik A, Mach T. Med Sci Monit. 2013 Apr 19;19:283-288.


  262. Correlation between degree and quality of sleep disturbance and the level of neuropsychiatric impairment in patients with liver cirrhosis
    Samanta J, Dhiman RK, Khatri A, Thumburu KK, Grover S, Duseja A, Chawla Y. Metab Brain Dis. 2013 Mar 15. [Epub ahead of print]


  263. Increased risk of cognitive impairment in cirrhotic patients with bacterial infections
    Merli M, Lucidi C, Pentassuglio I, Giannelli V, Giusto M, Gregorio VD, Pasquale C, Nardelli S, Lattanzi B, Venditti M, Riggio O. J Hepatol. 2013 Mar 21. pii: S0168-8278(13)00190-6. doi: 10.1016/j.jhep.2013.03.012. [Epub ahead of print]


  264. Hepatic encephalopathy associated with cancer or anticancer therapy
    Willson KJ, Nott LM, Broadbridge VT, Price T. Gastrointest Cancer Res. 2013 Jan;6(1):11-6.


  265. Update on cerebral uptake of blood ammonia
    Sørensen M. Metab Brain Dis. 2013 Mar 13. [Epub ahead of print]


  266. Altered Mental Status in Cirrhosis: Etiologies and Outcomes
    Rahimi RS, Elliott AC, Rockey DC. J Investig Med. 2013 Mar 7. [Epub ahead of print]


  267. Gut microbiota and hepatic encephalopathy
    Dhiman RK. Metab Brain Dis. 2013 Mar 6. [Epub ahead of print]


  268. Lactulose Is Highly Potential in Prophylaxis of Hepatic Encephalopathy in Patients with Cirrhosis and Upper Gastrointestinal Bleeding: Results of a Controlled Randomized Trial
    Wen J, Liu Q, Song J, Tong M, Peng L, Liang H. Digestion. 2013 Mar 6;87(2):132-138. [Epub ahead of print]


  269. Neurotransmitter receptor alterations in hepatic encephalopathy: A review
    Palomero-Gallagher N, Zilles K. Arch Biochem Biophys. 2013 Mar 1. pii: S0003-9861(13)00061-1. doi: 10.1016/j.abb.2013.02.010. [Epub ahead of print]


  270. End-stage liver disease complications
    Rahimi RS, Rockey DC. Curr Opin Gastroenterol. 2013 Feb 19. [Epub ahead of print]


  271. The effect of infections on the mortality of cirrhotic patients with hepatic encephalopathy
    Hung TH, Lay CJ, Chang CM, Tsai JJ, Tsai CC, Tsai CC. Epidemiol Infect. 2013 Feb 22:1-8. [Epub ahead of print]


  272. Effect of obstructive sleep apnea on the sleep architecture in cirrhosis
    Kappus MR, Leszczyszyn DJ, Moses L, Raman S, Heuman DM, Bajaj JS. J Clin Sleep Med. 2013 Mar 15;9(3):247-51. doi: 10.5664/jcsm.2488.


  273. Gastric Varices and Hepatic Encephalopathy: Treatment with Vascular Plug and Gelatin Sponge-assisted Retrograde Transvenous Obliteration--A Primary Report
    Gwon DI, Ko GY, Yoon HK, Sung KB, Kim JH, Shin JH, Ko HK, Song HY. Radiology. 2013 Mar 12. [Epub ahead of print]


  274. L-ornithine-L-aspartate for Hepatic Encephalopathy in Patients with Cirrhosis: A Meta-analysis of Randomized Controlled Trials
    Bai M, Yang Z, Qi X, Fan D, Han G. J Gastroenterol Hepatol. 2013 Feb 21. doi: 10.1111/jgh.12142. [Epub ahead of print]


  275. Serum Endotoxin, Inflammatory mediators and Magnetic Resonance Spectroscopy before and after treatment in patients with Minimal Hepatic Encephalopathy
    Jain L, Sharma BC, Srivastava S, Puri SK, Sharma P, Sarin S. J Gastroenterol Hepatol. 2013 Feb 21. doi: 10.1111/jgh.12160. [Epub ahead of print]


  276. Modulation of neural activation following treatment of hepatic encephalopathy
    McPhail MJ, Leech R, Grover VP, Fitzpatrick JA, Dhanjal NS, Crossey MM, Pflugrad H, Saxby BK, Wesnes K, Dresner MA, Waldman AD, Thomas HC, Taylor-Robinson SD. Neurology. 2013 Feb 20. [Epub ahead of print]


  277. Embolization of large spontaneous portosystemic shunts for refractory hepatic encephalopathy : A multi-center survey on safety & efficacy
    Laleman W, Simon-Talero M, Maleux G, Perez M, Ameloot K, Soriano G, Villalba J, Garcia-Pagan JC, Barrufet M, Jalan R, Brookes J, Thalassinos E, Burroughs AK, Cordoba J, Nevens F; on behalf of the EASL-CLIF-consortium. Hepatology. 2013 Feb 7. doi: 10.1002/hep.26314. [Epub ahead of print]


  278. The stroop smartphone APP is a short and valid method toscreen for minimal hepatic encephalopathy
    Bajaj JS, Thacker LR, Heuman DM, Fuchs M, Sterling RK, Sanyal AJ, Puri P, Siddiqui MS, Stravitz RT, Bouneva I, Luketic V, Noble N, White MB, Monteith P, Unser A, Wade JB. Hepatology. 2013 Feb 6. doi: 10.1002/hep.26309. [Epub ahead of print]


  279. Can the tyrosine kinase inhibitors trigger metabolic encephalopathy in cirrhotic patients?
    Brandi G, de Rosa F, Calzà L, Girolamo SD, Tufoni M, Ricci CS, Cirignotta F, Caraceni P, Biasco G. Liver Int. 2013 Mar;33(3):488-93. doi: 10.1111/liv.12102.


  280. Antibiotics for the treatment of hepatic encephalopathy
    Patidar KR, Bajaj JS. Metab Brain Dis. 2013 Feb 8. [Epub ahead of print]


  281. Acetyl-L-carnitine in hepatic encephalopathy
    Malaguarnera M. Metab Brain Dis. 2013 Feb 8. [Epub ahead of print]


  282. Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy
    Bak LK, Waagepetersen HS, Sørensen M, Ott P, Vilstrup H, Keiding S, Schousboe A. Metab Brain Dis. 2013 Jan 31. [Epub ahead of print]


  283. Altered effective connectivity network of the Basal Ganglia in low-grade hepatic encephalopathy: a resting-state FMRI study with granger causality analysis
    Qi R, Zhang LJ, Zhong J, Zhang Z, Ni L, Jiao Q, Liao W, Zheng G, Lu G. PLoS One. 2013;8(1):e53677. doi: 10.1371/journal.pone.0053677. Epub 2013 Jan 11


  284. Melatonin levels in serum and ascitic fluid of patients with hepatic encephalopathy
    Chojnacki C, Romanowski M, Winczyk K, B?asiak J, Chojnacki J. Gastroenterol Res Pract. 2012;2012:510764. doi: 10.1155/2012/510764. Epub 2012 Dec 30.


  285. Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy
    Görg B, Bidmon HJ, Häussinger D. Hepatology. 2013 Jan 16. doi: 10.1002/hep.26265. [Epub ahead of print]


  286. Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study
    Romeiro FG, da Silva Yamashiro F, Américo MF, Corá LA, Silva GF, Miranda J, Caramori CA. BMC Gastroenterol. 2013 Jan 16;13:13. doi: 10.1186/1471-230X-13-13.


  287. Current pathogenetic aspects of hepatic encephalopathy and noncirrhotic hyperammonemic encephalopathy
    Cicho?-Lach H, Michalak A. World J Gastroenterol. 2013 Jan 7;19(1):26-34. doi: 10.3748/wjg.v19.i1.26.


  288. Lack of Clostridium difficile Infection in Patients Treated With Rifaximin for Hepatic Encephalopathy: A Retrospective Analysis
    Neff GW, Jones M, Jonas M, Ravinuthala R, Novick D, Kaiser TE, Kemmer N. J Clin Gastroenterol. 2013 Feb;47(2):188-92. doi: 10.1097/MCG.0b013e318276be13.


  289. Pathogenesis of hepatic encephalopathy
    Cie?ko-Michalska I, Szczepanek M, S?owik A, Mach T. Gastroenterol Res Pract. 2012;2012:642108. doi: 10.1155/2012/642108. Epub 2012 Dec 17.


  290. Disrupted Functional Connectivity of the Anterior Cingulate Cortex in Cirrhotic Patients without Overt Hepatic Encephalopathy: A Resting State fMRI Study
    Zhang LJ, Qi R, Zhong J, Ni L, Zheng G, Xu J, Lu GM. PLoS One. 2013;8(1):e53206. doi: 10.1371/journal.pone.0053206. Epub 2013 Jan 7.


  291. Clinical Manifestations and Treatment Options in Patients with Cirrhosis and Diabetes Mellitus
    Gundling F, Seidl H, Strassen I, Haller B, Siegmund T, Umgelter A, Pehl C, Schepp W, Schumm-Draeger PM. Digestion. 2013 Jan 10;87(2):75-84. [Epub ahead of print]


  292. The continuous reaction times method for diagnosing, grading, and monitoring minimal/covert hepatic encephalopathy.
    Metab Brain Dis. 2013 Jan 10. [Epub ahead of print] Lauridsen MM, Thiele M, Kimer N, Vilstrup H.


  293. Lactulose, rifaximin or branched chain amino acids for hepatic encephalopathy: what is the evidence?
    Gluud LL, Dam G, Borre M, Les I, Cordoba J, Marchesini G, Aagaard NK, Vilstrup H. Metab Brain Dis. 2012 Dec 29. [Epub ahead of print]


  294. Glutamine in the Pathogenesis of Hepatic Encephalopathy: The Trojan Horse Hypothesis Revisited
    Rama Rao KV, Norenberg MD. Neurochem Res. 2013 Jan 1. [Epub ahead of print]


  295. Comparison of the most favoured methods for the diagnosis of hepatic encephalopathy in liver transplantation candidates
    Goldbecker A, Weissenborn K, Hamidi Shahrezaei G, Afshar K, Rümke S, Barg-Hock H, Strassburg CP, Hecker H, Tryc AB. Gut. 2013 Jan 7. [Epub ahead of print]


  296. Depression, anxiety and alexithymia symptoms are major determinants of health related quality of life (HRQoL) in cirrhotic patients
    Nardelli S, Pentassuglio I, Pasquale C, Ridola L, Moscucci F, Merli M, Mina C, Marianetti M, Fratino M, Izzo C, Merkel C, Riggio O. Metab Brain Dis. 2013 Jan 8. [Epub ahead of print]


  297. How to diagnose hepatic encephalopathy in the emergency department
    Gundling F, Zelihic E, Seidl H, Haller B, Umgelter A, Schepp W, Dodt C. Ann Hepatol. 2013 Jan;12(1):108-14.


  298. Meta-analysis: the diagnostic accuracy of critical flicker frequency in minimal hepatic encephalopathy
    Torlot FJ, McPhail MJ, Taylor-Robinson SD. Aliment Pharmacol Ther. 2013 Jan 7. doi: 10.1111/apt.12199. [Epub ahead of print]


  299. Resting State Cortical Electroencephalographic Rhythms in Covert Hepatic Encephalopathy and Alzheimer's Disease
    Babiloni C, Vecchio F, Del Percio C, Montagnese S, Schiff S, Lizio R, Chini G, Serviddio G, Marzano N, Soricelli A, Frisoni GB, Rossini PM, Amodio P. J Alzheimers Dis. 2012 Dec 27. [Epub ahead of print]


  300. Increased Incidence of Orthopedic Fractures in Cirrhotic Patients: A Nationwide Population-Based Study
    Tsai CF, Liu CJ, Chen TJ, Chu CJ, Lin HC, Lee FY, Su TP, Lu CL. J Hepatol. 2012 Dec 10. pii: S0168-8278(12)00919-1. doi: 10.1016/j.jhep.2012.12.001. [Epub ahead of print]


  301. Prevention and treatment of hepatic encephalopathy: Focusing on gut microbiota
    Garcovich M, Zocco MA, Roccarina D, Ponziani FR, Gasbarrini A. World J Gastroenterol. 2012 Dec 14;18(46):6693-700. doi: 10.3748/wjg.v18.i46.6693.


  302. Changes in expression of the chloride homeostasis-regulating genes, KCC2 and NKCC1, in the blood of cirrhotic patients with hepatic encephalopathy
    Li JJ, Ji R, Shi YQ, Wang YY, Yang YL, Dou KF. Exp Ther Med. 2012 Dec;4(6):1075-1080. Epub 2012 Sep 24.


  303. Muscle depletion increases the risk of overt and minimal hepatic encephalopathy: results of a prospective study
    Merli M, Giusto M, Lucidi C, Giannelli V, Pentassuglio I, Di Gregorio V, Lattanzi B, Riggio O. Metab Brain Dis. 2012 Dec 7. [Epub ahead of print]
 
 
                               
 
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