Author information

1 Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China. xiaoyuanxu6@163.com.

2 Hepatology and Digestion Center, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.

3 Department of Liver Oncology, Cancer Radiation Therapy Center, Fifth Medical Center, PLA General Hospital, Beijing 100039, China.

4 Hepatology Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

5 Hepatobiliary and Pancreatic Department, Beijing Tsinghua Changgeng Hospital, Beijing 102218, China.

6 Artificial Liver Center, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.

7 Department of Gastroenterology, Peking University People's Hospital, Beijing 100044, China.

8 Department of Gastroenterology, First Medical Center, PLA General Hospital, Beijing 100853, China.

9 Department of Pathogenic Biology, Peking University Health Science Center, Beijing 100191, China.

Abstract

The Chinese Society of Hepatology developed the current guidelines on the management of hepatic encephalopathy in cirrhosis based on the published evidence and the panelists' consensus. The guidelines provided recommendations for the diagnosis and management of hepatic encephalopathy (HE) including minimal hepatic encephalopathy (MHE) and overt hepatic encephalopathy, emphasizing the importance on screening MHE in patients with end-stage liver diseases. The guidelines emphasized that early identification and timely treatment are the key to improve the prognosis of HE. The principles of treatment include prompt removal of the cause, recovery of acute neuropsychiatric abnormalities to baseline status, primary prevention, and secondary prevention as soon as possible.