1 Dr Hershman is a fellow in the Division of Gastroenterology at Mount Sinai Beth Israel, Mount Sinai St. Luke's, and Mount Sinai West in New York, New York. Ms Mei is a medical student at the Icahn School of Medicine at Mount Sinai in New York, New York. Dr Kushner is an assistant professor of medicine in the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai.
With an estimated 10% prevalence of nonalcoholic fatty liver disease (NAFLD) among women of childbearing age, it is important to understand the implications of this disease on pregnancy. This article explores the relationship between NAFLD and gestational diabetes mellitus, the implications of maternal NAFLD on both the pregnancy and the infant, and the effects of breastfeeding on maternal and offspring health. Prospective studies and sensitive diagnostic techniques for the evaluation of NAFLD during pregnancy are limited; however, emerging evidence suggests that appropriate counseling and monitoring of patients with, or at risk of developing, NAFLD during pregnancy may have significant benefits on maternal and child health.