Author information

¹Family Health Centers of San Diego, San Diego, California, USA.

²Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.

³Department of Gastroenterology/Hepatology, Henry Ford Health, Detroit, Michigan, USA.

⁴Division of Gastroenterology and Hepatology, Veterans Affairs Palo Alto Health Care System and Stanford University School of Medicine, Palo Alto, California, USA.

⁵Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.

⁶Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Chicago Medical Center, University of Chicago, Chicago, Illinois, USA.

Abstract

Focal liver lesions (FLLs) have become an increasingly common finding on abdominal imaging, especially asymptomatic and incidental liver lesions. Gastroenterologists and hepatologists often see these patients in consultation and make recommendations for management of multiple types of liver lesions, including hepatocellular adenoma, focal nodular hyperplasia, hemangioma, and hepatic cystic lesions including polycystic liver disease. Malignancy is important to consider in the differential diagnosis of FLLs, and healthcare providers must be familiar with the diagnosis and management of FLLs. This American College of Gastroenterology practice guideline uses the best evidence available to make diagnosis and management recommendations for the most common FLLs.