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Abstract Details
Expanding the immunotherapy roadmap for hepatocellular carcinoma
Cancer Cell. 2022 Mar 14;40(3):252-254. doi: 10.1016/j.ccell.2022.02.017.
Marina Baretti1, Amy K Kim2, Robert A Anders3
Author information
Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: rander54@jhmi.edu.
Abstract
In a recent Lancet Oncology article, Yau et al. report the CheckMate 459 trial results. This is the first phase III trial comparing the single-agent anti-programmed death protein 1 (PD-1) therapy nivolumab to the tyrosine kinase inhibitor sorafenib for treatment-naive patients with advanced hepatocellular carcinoma.
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