1ITAB-Institute of Advanced Biomedical Technologies, "9301G. d'Annunzio" University, Chieti, Italy.
2Department of Neuroscience, Imaging and Clinical Sciences, "9301G. d'Annunzio" University, Chieti, Italy.
3Department of Radiology, 10624Stanford University School of Medicine, Stanford, CA, USA.
The Liver Imaging Reporting and Data System (LI-RADS) is a recently developed classification aiming to improve the standardization of liver imaging assessment in patients at risk of developing hepatocellular carcinoma (HCC). The LI-RADS v2017 implemented new algorithms for ultrasound (US) screening and surveillance, contrast-enhanced US diagnosis and computed tomography/magnetic resonance imaging treatment response assessment. A minor update of LI-RADS was released in 2018 to comply with the American Association for the Study of the Liver Diseases guidance recommendations. The scope of this review is to provide a practical overview of LI-RADS v2018 focused both on the multimodality HCC diagnosis and treatment response assessment.