Department of Mathematics, University of Sussex, Brighton BN1 9QH, UK.
Department of Mathematics, University of Sussex, Brighton BN1 9QH, UK. Electronic address: firstname.lastname@example.org.
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a chronic infection, or periodic oscillations. Effects of nucleoside analogues and interferon treatments are analysed, and the critical drug efficiency is determined.