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Abstract Details
Pediatric biliary disorders: Multimodality imaging evaluation with clinicopathologic correlation
Clin Imaging. 2021 Jan 21;75:34-45. doi: 10.1016/j.clinimag.2021.01.006.Online ahead of print.
Hassan Aboughalia1, Helen Hr Kim2, Andre A S Dick3, M Cristina Pacheco4, Robert E Cilley5, Ramesh S Iyer6
Author information
1Radiology Department, University of Washington Medical Center, Seattle, WA 98195, United States of America. Electronic address: ghalia@uw.edu.
2Radiology Department, Seattle Children's Hospital, University of Washington School of Medicine, 98105, United States of America. Electronic address: HelenHR.kim@seattlechildrens.org.
3Department of Surgery, Section of Pediatric Transplant, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, 98105, United States of America. Electronic address: docdre@uw.edu.
4Department of Pathology, University of Washington, Department of Laboratories, Seattle Children's Hospital, United States of America. Electronic address: Cristina.pacheco@seattlechildrens.org.
5Children's Surgery Center, Penn State Children's Hospital, Milton S. Hershey Medical Center, United States of America. Electronic address: rcilley@pennstatehealth.psu.edu.
6Radiology Department, Seattle Children's Hospital, University of Washington School of Medicine, 98105, United States of America. Electronic address: riyer@uw.edu.
Abstract
The spectrum of pathologies affecting the biliary tree in the pediatric population varies depending on the age of presentation. While in utero insults can result in an array of anatomic variants and congenital anomalies in newborns, diverse acquired biliary pathologies are observed in older children. These acquired pathologies display different presentations and consequences than adults. Multimodality imaging assessment of the pediatric biliary system is requisite to establishing an appropriate management plan. Awareness of the imaging features of the various biliary pathologies and conveying clinically actionable information is essential to facilitate appropriate patient management. In this paper, we will illustrate the anatomy and embryology of the pediatric biliary system. Then, we will provide an overview of the imaging modalities used to assess the biliary system. Finally, we will review the unique features of the pediatric biliary pathologies, complemented by histopathologic correlation and discussions of clinical management.