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Abstract Details
From hepatitis A to E: A critical review of viral hepatitis
World J Gastroenterol. 2021 Apr 28;27(16):1691-1715. doi: 10.3748/wjg.v27.i16.1691.
Daniel Castaneda1, Adalberto Jose Gonzalez2, Mohammad Alomari2, Kanwarpreet Tandon2, Xaralambos Bobby Zervos3
Author information
1Digestive Disease Institute, Cleveland Clinic Florida, Weston, FL 33331, United States. daniel.castaneda.m@gmail.com.
2Digestive Disease Institute, Cleveland Clinic Florida, Weston, FL 33331, United States.
3Transplant Department, Cleveland Clinic Florida, Weston, FL 33331, United States.
Abstract
Viral infections affecting the liver have had an important impact on humanity, as they have led to significant morbidity and mortality in patients with acute and chronic infections. Once an unknown etiology, the discovery of the viral agents triggered interest of the scientific community to establish the pathogenesis and diagnostic modalities to identify the affected population. With the rapid scientific and technological advances in the last centuries, controlling and even curing the infections became a possibility, with a large focus on preventive medicine through vaccination. Hence, a comprehensive understanding of hepatitis A, B, C, D and E is required by primary care physicians and gastroenterologists to provide care to these patients. The review article describes the epidemiology, pathogenesis, clinical presentation, diagnostic tools and current medication regimens, with a focus on upcoming treatment options and the role of liver transplantation.