1Artificial Liver Treatment and Training Center, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
2Faculty of Health Sciences, University of Macau, Macao, SAR, China.
3The University of Notre Dame Australia/Marian Centre, Perth, Australia.
4Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, New York, USA.
5Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia.
6Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China.
To determine the frequency and socio-demographic/clinical correlates of insomnia in patients with chronic hepatitis B, hepatitis B virus (HBV)-related liver failure, and cirrhosis.
DESIGN AND METHODS:
Up to 120 patients with HBV-related diseases and 40 matched healthy controls were recruited. Depressive and anxiety symptoms, early, middle, and late insomnia were measured.
The frequency of ≥1 type of insomnia was 64.2% in patients and 35.0% in controls; frequencies of early, middle, and late insomnia in patients were 39.2%, 42.5%, and 48.3%, respectively, compared to 22.5%, 10.0%, and 25.0% in controls. Urban residency was independently associated with less insomnia of any type, accounting for 22.6% of the variance.
A considerable proportion of patients with HBV-related diseases suffer from insomnia that warrants more attention in clinical practice.